Hypothalamus and Pituitary is part of the Endocrine System section of Pharmacology. Practise 12 exam-style MCQs for NEET PG, FMGE, INI-CET and NEET SS, each with the correct answer and a detailed explanation.
Hypothalamus and Pituitary MCQs revisit bromocriptine for hyperprolactinaemia, somatostatin analogues in acromegaly, GnRH analogues in precocious puberty and growth hormone resistance. A high-yield NEET PG set on pituitary axes and their drug levers.
Sample Hypothalamus and Pituitary MCQs with answers
Sample MCQ #1
A 32-year-old woman with amenorrhea, infertility, and galactorrhea is treated with a drug that known to successfully restore ovulation and menstruation. She is advised to take the drug ,Bromocriptine orally. Before being given the drug, What you'll question the woman about previous/present history?
ASchizophrenia
BTremor
CRecent Covid19 infection
DRecent neurosurgery
Show Answer & Explanation ▾
✓ Correct Answer: A. Schizophrenia
Bromocriptine, a dopamine receptor agonist, is used to treat the amenorrhea-galactorrhea syndrome, which is a consequence of hyperprolactinemia. Because of its central dopaminergic effects, the drug should not be used in patients with a history of schizophrenia or other forms of psychotic illness. Reference: Basic & Clinical Pharmacology, Fourteenth Edition By Bertram G. Katzung Pg no. 680, 725
Sample MCQ #2
A 47-year-old man exhibited signs and symptoms of acromegaly. Radiologic studies indicated the presence of a large pituitary tumor. Surgical treatment of the tumor was only partially effective in controlling his disease. At this point, which of the following drugs is most likely to be used as pharmacologic therapy?
ASomatropin
BDesmopressin
CLeuprolide
DOctreotide
Show Answer & Explanation ▾
✓ Correct Answer: D. Octreotide
The medicines most often used to treat acromegaly are called somatostatin analogs (SSAs) like octreotide. These drugs curb the release of GH and may also reduce the size of the pituitary tumor. Several studies have shown that these drugs are safe and effective for long-term treatment. Reference: Basic & Clinical Pharmacology, Fourteenth Edition By Bertram G. Katzung Pg no. 675
Sample MCQ #3
A 26-year-old woman presents with amenorrhea and galactorrhea. Her prolactin level is grossly elevated (200 ng/mL). Which of the following is most useful in the treatment of hyperprolactinemia?
ABromocriptine
BCimetidine
CErgotamine
DKetanserin
Show Answer & Explanation ▾
✓ Correct Answer: A. Bromocriptine
Bromocriptine is an effective dopamine agonist in the CNS with the advantage of oral activity. The drug inhibits prolactin secretion by activating pituitary dopamine receptors. Reference: Basic & Clinical Pharmacology, Fourteenth Edition By Bertram G. Katzung Pg no. 286
Sample MCQ #4
A 4-year-old girl presented with hirsutism, breast enlargement, and a height and bone age that was consistent with an age of 9. Which of the following is the most appropriate drug for treatment of this patient ?
AAtosiban
BFollitropin
CLeuprolide
DPegvisomant
Show Answer & Explanation ▾
✓ Correct Answer: C. Leuprolide
Given clinical scenario suggest the diagnosis of precocious puberty. Treatment involves suppressing gonadotropin secretion with continuous administration of a long-acting GnRH agonist such as leuprolide. Reference: Basic & Clinical Pharmacology, Fourteenth Edition By Bertram G. Katzung Pg no.622
Sample MCQ #5
A 2-year-old boy with failure to thrive was found to have an inactivating mutation in the gene that encodes the growth hormone receptor. Which of the following drugs is most likely to improve his metabolic function and promote his growth?
AAtosiban
BBromocriptine
CMecasermin
DSomatropin
Show Answer & Explanation ▾
✓ Correct Answer: C. Mecasermin
This child’s condition is due to the inability of GH to stimulate the production of insulin-like growth factors, the ultimate mediators of GH effects. Mecasermin, a combination of recombinant IGF-1 and the binding protein that protects IGF-1 from immediate destruction, will help correct the IGF deficiency. Because of the inactive GH receptors, somatropin will not be effective. Reference: Basic & Clinical Pharmacology, Fourteenth Edition By Bertram G. Katzung Pg. no. 678
What you can practise in Hypothalamus and Pituitary
12 Hypothalamus and Pituitary MCQs on Hypothalamus, Pituitary, Endocrine System — each with detailed explanations
Previous-year question practice across NEET PG, FMGE, INI-CET and NEET SS
Progress and performance tracking to measure retention
Hypothalamus and Pituitary MCQs revisit bromocriptine for hyperprolactinaemia, somatostatin analogues in acromegaly, GnRH analogues in precocious puberty and growth hormone resistance. A high-yield NEET PG set on pituitary axes and their drug levers.
How many Hypothalamus and Pituitary questions are there, and which exams do they cover?
MedLadder includes 12 curated MCQs for Hypothalamus and Pituitary under Pharmacology (Endocrine System), covering NEET PG, FMGE, INI-CET and NEET SS preparation.
