Intracellular Accumulations, Pathological Calcification and Cellular Ageing MCQs
Intracellular Accumulations, Pathological Calcification and Cellular Ageing is part of the General Pathology section of Pathology. Practise 67 exam-style MCQs for NEET PG, FMGE, INI-CET and NEET SS, each with the correct answer and a detailed explanation.
About Intracellular Accumulations, Pathological Calcification and Cellular Ageing MCQs
Intracellular Accumulations, Pathological Calcification and Cellular Ageing MCQs move from lipofuscin, haemosiderin and melanin pigments to dystrophic calcification and the Hayflick limit on cell division. This high-yield NEET PG collection suits steady revision for FMGE, INI-CET and NEET SS.
Sample Intracellular Accumulations, Pathological Calcification and Cellular Ageing MCQs with answers
Sample MCQ #1
A 65-year-old male patient having long-standing cigarette smoking (2 pkt/day) and nonfebrile presented to OPD complaints of shortness of breath and cough since many months. His dyspneic duration and intensity increasing these days. His chest is hyperresonant on percussion. Clubbing is also present. X-ray revealed overinflation of lung. Based on the above findings, what will be the histopathological findings in the lung?
ADestruction of the walls of airspaces without fibrosis
✓ Correct Answer: A. Destruction of the walls of airspaces without fibrosis
Emphysema is a chronic lung disease characterized by enlargement of the airspaces distal to the terminal bronchioles, with destruction of their walls, but without fibrosis or inflammation. Reference: Robbins & Cotran Pathologic Basis of Diseases 10 th edition Chapter-15, Pg 678
Sample MCQ #2
Which concept states that a normal human cell can only replicate and divide forty to sixty times before it cannot divide anymore, and will break down by programmed cell death or apoptosis?
AHayflick limit
BGompertzian phenomenon
COncogene addiction
DSigma graph
Show Answer & Explanation ▾
✓ Correct Answer: A. Hayflick limit
B and c are realetd to neoplasia and d is related to quality control Reference: Robbins & Cotran Pathologic Basis of Diseases 10 th edition, Chapter - 2 pg 42
Sample MCQ #3
Which pathological process is the reason of release of cardiac specific enzymes in blood?
AAutophagy
BNecroptosis
CApoptosis
DNecrosis
Show Answer & Explanation ▾
✓ Correct Answer: D. Necrosis
The biochemical mechanisms of necrosis vary with different injurious stimuli. These mechanisms include: Failure of energy generation in the form of ATP because of reduced oxygen supply or mitochondrial damage Damage to cellular membranes, including the plasma membrane and lysosomal membranes, which results in leakage of cellular contents including enzymes Irreversible damage to cellular lipids, proteins and nucleic acids, which may be caused by reactive oxygen species (ROS); and others. Reference: Robbins and Cotran Pathologic Basis of Diseases, 10 th ed Pg:35
Sample MCQ #4
Assertion: Dystrophic calcification is associated with necrosis Reason: Serum calcium level is high in Dystrophic calcification
ABoth statements are true and causally related
BBoth statements are true but not causally related
CThe first statement is true and second is false
DThe first statement is false and second is true
Show Answer & Explanation ▾
✓ Correct Answer: C. The first statement is true and second is false
Dystrophic calcification: In this form, calcium metabolism is normal but it deposits in injured or dead tissue, such as areas of necrosis of any type. Reference: Robbins and Cotran Pathologic Basis of Diseases, 10 th ed Pg:53
Sample MCQ #5
Assertion: Most common exogenous pigment is carbon. Reason: Most common endogenous pigment is lipofuschin.
ABoth statements are true and causally related
BBoth statements are true but not causally related
CThe first statement is true and second is false
DThe first statement is false and second is true
Show Answer & Explanation ▾
✓ Correct Answer: B. Both statements are true but not causally related
Pigments are colored substances that are either exogenous, coming from outside the body, such as carbon or are endogenous, synthesized within the body itself, such as lipofuscin, melanin and certain derivatives of hemoglobin. Reference: Robbins and Cotran Pathologic Basis of Diseases, 10 th ed Pg:52
Sample MCQ #6
Principle of Prussian blue stain:
AFerrous to ferricyanide
BFerricyanide to ferroferric cyanide
CFerroferriccyanide to ferrocyanide
DFerrocyanide to ferricferrocyanide
Show Answer & Explanation ▾
✓ Correct Answer: D. Ferrocyanide to ferricferrocyanide
Hemosiderin reacts with potassium ferrocyanide to form a blue compound, ferri ferrocyanide; this reaction is the basis of a positive Prussian-blue (Perls’) reaction. Reference: Robbins& Cotran Pathologic Basis of Diseases 10 th edition, Chapter - 2 pg 44
Sample MCQ #7
Which of the following pigment is called the 'wear and tear' pigment?
ALipofuscin pigment
BHemosiderin pigment
CBile pigment
DFormalin pigment
Show Answer & Explanation ▾
✓ Correct Answer: A. Lipofuscin pigment
Lipofuscin pigment is called as the "wear and tear" pigment Reference: Robbins and Cotran Pathologic Basis of Diseases, 10 th ed Pg:52
Sample MCQ #8
Which of the following pigments are hematogenous? i. Hemosiderin pigment ii. Bile pigment iii. Porphyrin pigment iv. Melanin pigment
AOnly i, ii and iii are correct
BOnly i and iii are correct
COnly ii and iv are correct
DOnly iv is correct
Show Answer & Explanation ▾
✓ Correct Answer: B. Only i and iii are correct
Melanin is an endogenous, brown-black pigment that is synthesized by melanocytes located in the epidermis and acts as a screen against harmful UV radiation. Although melanocytes are the only source of melanin. Reference: Robbins and Cotran Pathologic Basis of Diseases, 10 th ed Pg:52
What you can practise in Intracellular Accumulations, Pathological Calcification and Cellular Ageing
67 Intracellular Accumulations, Pathological Calcification and Cellular Ageing MCQs on Intracellular Accumulations, Pathological Calcification, Cellular Ageing — each with detailed explanations
Previous-year question practice across NEET PG, FMGE, INI-CET and NEET SS
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What do Intracellular Accumulations, Pathological Calcification and Cellular Ageing MCQs cover?
Intracellular Accumulations, Pathological Calcification and Cellular Ageing MCQs move from lipofuscin, haemosiderin and melanin pigments to dystrophic calcification and the Hayflick limit on cell division. This high-yield NEET PG collection suits steady revision for FMGE, INI-CET and NEET SS.
How many Intracellular Accumulations, Pathological Calcification and Cellular Ageing questions are there, and which exams do they cover?
MedLadder includes 67 curated MCQs for Intracellular Accumulations, Pathological Calcification and Cellular Ageing under Pathology (General Pathology), covering NEET PG, FMGE, INI-CET and NEET SS preparation.
