Non Syphilitic Sexually Transmitted Diseases MCQs

Primary Stage: The patient characteristically develops a painless genital ulcer or papules which are about 1 to 6 mm in size. secondary stage presents with the development of unilateral or bilateral tender inguinal and/or femoral lymphadenopathy (also called buboes), which occurs two to six weeks after the primary stage; this is called the inguinal syndrome. Late stage : necrosis of lymph node when left untreated. Reference: Rooks textbook of dermatology, 9 th edition, chapter 30, page 17

As a PHC MO, follow the guidelines of syndromic management NACO guidelines. According to it, a painful genital ulcer patient should be given red kit- kit no. 5 It contains tab acyclovir 400mg. Dose : Three tablets a day for 7 days (21 tablets total) Reference: NACO guidelines for Syndromic Management of STI

DGI occurs when the sexually transmitted pathogen Neisseria gonorrhoeae invades the bloodstream and spreads to distant sites in the body, leading to clinical findings such as septic arthritis, polyarthralgia, tenosynovitis, petechial/pustular skin lesions, bacteremia, or, on rare occasions, endocarditis or meningitis. The classic triad of features consists of dermatitis, tenosynovitis and migratory polyarthritis DGI is uncommon and thought to occur in 0.5-3% of untreated gonorrhea cases. Reference: Rooks textbook of dermatology, chapter 30, page 5

Genital herpes MC ulcerative STI among adolescents, is a chronic, lifelong viral infection Two sexually transmitted HSV types have been identified, HSV-1 and HSV-2 Majority of cases of recurrent genital herpes are caused by HSV-2, which is also called HHV2 Reference: Rooks textbook of dermatology, 9 th edition, chapter 25, page 20

Trachomatis isolates exist as 15 serovariants. Trachoma - ocular tropic strains (A, B, Ba, and C) Genitourinary tract tropic (D, E, F, G, H, I, J, and K) strains Invasive lymphogranuloma venereum (L1, L2, and L3) The causative agent of LGV is Chlamydia trachomatis serovars L1-L3. Reference: Rooks textbook of dermatology, 9 th edition, chapter 30, page 16

Granuloma Inguinale Genital ulcerative disease caused by the intracellular gram-negative bacterium Klebsiella granulomatis (formerly known' as Calymmatobacterium granulomatis) Painless, slowly progressive ulcerative lesions on the genitals or perineum without regional lymphadenopathy, subcutaneous granulomas (Pseudo buboes) Lesions are highly vascular (beefy red appearance) and bleed on touch Reference: Rooks textbook of dermatology, 9 th edition, chapter 30, page 25

The secondary stage presents with the development of unilateral or bilateral tender inguinal and/or femoral lymphadenopathy (also called buboes), which occurs two to six weeks after the primary stage; this is called the inguinal syndrome. An anorectal syndrome also presents which is characterized by proctitis or proctocolitis-like symptoms. Pain during urination, rectal bleeding, pain during passing stools, abdominal pain, anal pain, tenesmus. Generalized symptoms like body aches, headache, and fever can occur during this stage. This syndrome usually occurs when the transmission is via the anal route. An oral syndrome can occur in people get LGV through the oral route. Cervical lymphadenopathy can occur. There are also reports of systemic complications like pneumonia and hepatitis. Reference: Rooks textbook of dermatology, 9 th edition, chapter 30, page 18

Bacterial vaginosis is not considered as an STI. It is usually caused by imbalance between aerobic and anaerobic flora of the vagina. However it is mostly seen in sexually active women, with new partner or multiple partners. It is rare in virgins. REFERENCE: Rooks textbook of dermatology, chapter 31