Acne, Rosacea and Others MCQs

Syringomas are benign, eccrine sweat duct tumours, typically found clustered on eyelids in a symmetric pattern. Syringomas are skin-coloured or yellowish, generally small, dermal papules. Reference: Rook's Textbook of Dermatology, 9th Edition, Page Number-30.

Clinical Presentation of Acne Sites: Face, shoulders, upper trunk Polymorphic eruption: Comedones, papules, nodules, cysts Comedones: Pathognomonic lesions of acne vulgaris Open comedones (Black heads): Block on skin surface Closed comedones (White heads): Block below skin surface Reference: Rook’s Textbook of Dermatology, 9th Edition, Chapter 90, Page 1

Rhinophyma is a disfiguring nasal deformity due to the proliferation of sebaceous glands and underlying connective tissue. The name itself is broken down into "rhis," derived from Greek meaning nose, and "phyma," also Greek, for skin tumor. Rosacea is the precursor condition to the later development of rhinophyma Rhinophyma has no malignant potential Reference: Rooks textbook of dermatology, chapter 142, page 142.1

Acne inversa is another name for Hidradenitis Suppurativa HS can be associated with other follicular occlusion diseases such as pilonidal cysts (PCs) of the sacrum and buttocks, dissecting cellulitis (DC), and acne conglobata (AC), which usually involves the face, chest. PCs, DC, and/or AC - the follicular occlusion triad When HS occurs with PCs, DC, and/or AC it is referred to as the follicular occlusion tetrad. Reference: Rook’s Textbook of Dermatology, 9th Edition, Chapter 92, Page 2

Rosacea is defined as a chronic disease that impacts fair skinned middle aged adults. This chronic disease is characterized as telangiectasia and flushing in early stage, pustules and papules in inflammatory stage, papules and induction and rhinophyma in chronic stage Reference: Rook’s Textbook of Dermatology, 9th Edition, Chapter 91, Page 2

Differential diagnosis of Rosacea includes Acne vulgaris, Seborrheic dermatitis, Perioral dermatitis, Carcinoid syndrome, Lupus erythematosus, Basal cell carcinoma Most common potential diagnostic confusion is between rosacea and acne vulgaris, owing to the presence of pustules and papules. Reference: Rook’s Textbook of Dermatology, 9th Edition, Chapter 91, Page 10

Explanation: Blue discolouration of skin is not a side effect of corticosteroids Topical corticosteroids cause a variety of local adverse effects due to dermal atrophy and altered follicular activity. (Mneumonic - STEROID ) S - Skin thinning ( atrophy , striae) (Option 2 is true) T-; Telangiectasia E - Ecchymosis (easy bruising) R -; Rosacea-like dermatitis O - Opportunistic infections (folliculitis, tinea incognito) I - Induced acne ( steroid acne ), Increased hair growth ( hypertrichosis ) (Option 3 and 4 are true) D -; Decreased pigmentation and Delayed wound healing Key Takeaway: Bluish-Grey Discolouration of Skin (Ceruloderma) is caused by Antiarrhythmic: Amiodarone Antibiotics: Minocycline Antimalarials: Hydroxychloroquine, Chloroquine Silver compounds: Argyria Antipsychotic: Chlorpromazine

Incidences of Squamous cell, carcinoma, Basal cell carcinoma, and Actinic keratosis are markedly increased in patients with Oculocutaneous albinism. Retinoids like isotretinoin are effective as chemopreventive agents in premalignant lesions of the skin. If retinoids are given at an early stage, they can cause regression of premalignant lesions of the skin. These can be recommended as they reduce the potential effects of carcinogenesis. Reference: Rooks textbook of Dermatology, 9 th edition, chapter 70, page 8