Parasympathomimetics & Cholinergic Agonists is part of the Autonomic Nervous System section of Pharmacology. Practise 66 exam-style MCQs for NEET PG, FMGE, INI-CET and NEET SS, each with the correct answer and a detailed explanation.
Sample Parasympathomimetics & Cholinergic Agonists MCQs with answers
Sample MCQ #1
A 28-year-old woman presents with recent onset of weakness of her hands, diplopia, and difficulty swallowing. She has been treated for myasthenia gravis for several years. Which of the following is the best drug for distinguishing between myasthenic crisis and cholinergic crisis ?
AAtropine
BEdrophonium
CPhysostigmine
DPyridostigmine
Show Answer & Explanation ▾
✓ Correct Answer: B. Edrophonium
Any of the cholinesterase inhibitors (choices B, C, or D) would effectively correct myasthenic crisis. However, because cholinergic crisis (if that is what is causing the symptoms) would be worsened by a cholinomimetic, we choose the shortest-acting cholinesterase inhibitor, edrophonium. Reference: Basic & Clinical Pharmacology, Fourteenth Edition By Bertram G. Katzung Pg no. 113
Sample MCQ #2
A 45-year-old farmer is admitted for Parathion poisoning. Which one of the following is its characteristics?
AIf treated early, its toxicity may be partly reversed by pralidoxime
BIt is less toxic to humans than malathion
CIt is more persistent in the environment than DDT
DIt is poorly absorbed through skin and lungs
Show Answer & Explanation ▾
✓ Correct Answer: A. If treated early, its toxicity may be partly reversed by pralidoxime
The "-thion" organophosphates (those containing the P=S bond) are activated, not inactivated, by conversion to "-oxon" (P=O) derivatives. They are less stable than halogenated hydrocarbon insecticides of the DDT type; therefore, they are less persistent in the environment. Parathion is more toxic than malathion. It is very lipid-soluble and rapidly absorbed through the lungs and skin. Pralidoxime has very high affinity for the phosphorus atom and is a chemical antagonist of organophosphates. Reference: Basic & Clinical Pharmacology, Fourteenth Edition By Bertram G. Katzung Pg no. 115
Sample MCQ #3
A 30-year-old woman complains of severe bloating after undergoing abdominal surgery. She also finds it difficult to urinate. Mild cholinomimetic stimulation without vasodilation is preferred for treatment. Which agent should be preferred ?
ABethanechol
BDistigmine
CCevimeline
DCarbachol
Show Answer & Explanation ▾
✓ Correct Answer: B. Distigmine
Bethanechol or distigmine is often effective in relieving post-op ileus. Neostigmine and bethanechol in moderate doses have significantly different effects on vascular endothelium. Bethanechol directly acts on muscarinic receptor of vascular endothelium and cause vasodilation, while Distigmine, Indirectly acting AchE inhibitor, does not cause vasodilation. Reference: Basic & Clinical Pharmacology, Fourteenth Edition By Bertram G. Katzung Pg no. 132
What you can practise in Parasympathomimetics & Cholinergic Agonists
66 Parasympathomimetics & Cholinergic Agonists MCQs on Parasympathomimetics, Cholinergic Agonists, Autonomic Nervous System — each with detailed explanations
Previous-year question practice across NEET PG, FMGE, INI-CET and NEET SS
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How many questions are in Parasympathomimetics & Cholinergic Agonists?
MedLadder includes 66 curated MCQs with explanations for Parasympathomimetics & Cholinergic Agonists under Pharmacology (Autonomic Nervous System).
Which medical exams does this topic prepare for?
These Pharmacology questions prepare you for FMGE, NEET PG, INI-CET, and NEET SS, covering both conceptual MCQs and clinical scenarios.
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