Anti-Protozoal Agents and Anthelmintic Drugs is part of the Antimicrobials section of Pharmacology. Practise 23 exam-style MCQs for NEET PG, FMGE, INI-CET and NEET SS, each with the correct answer and a detailed explanation.
About Anti-Protozoal Agents and Anthelmintic Drugs MCQs
Anti-Protozoal Agents and Anthelmintic Drugs MCQs run from metronidazole in amoebiasis and neurocysticercosis steroids to albendazole dosing, ivermectin and DEC in filariasis. These high-yield NEET PG questions on parasites, worms and their drug targets.
Sample Anti-Protozoal Agents and Anthelmintic Drugs MCQs with answers
Sample MCQ #1
Pyrantel pamoate is not effective against______________.
APinworm, Ascaris
BHookworm
CTrichuriasis, strongyloidiasis
DAll of the above
Show Answer & Explanation ▾
✓ Correct Answer: C. Trichuriasis, strongyloidiasis
Pyrantel pamoate is a broad-spectrum antihelminthic highly effective for the treatment of pinworm, ascaris, and Trichostrongylus orientalis It is moderately effective against both species of hookworm. It is not effective in trichuriasis or strongyloidiasis. Oxantel pamoate, an analog of pyrantel not available in the USA, has been used successfully in the treatment of trichuriasis; the two drugs have been combined for their broad-spectrum antihelminthic activity Reference: LANG' Basic & clinical pharmacology by Bertram G. Katzung, Susen B. Masters and Anthony J. Trevor 12 th edition. Chapter 53-Clinical Pharmacology of the Antihelminthic Drugs by Dr. Philip J. Rosenthal, MD. Page no. 945
Sample MCQ #2
What is the maximum dose of pyrantel that can be given in one day?
A0.5 gm
B1 gm
C2 gm
DNone of the above
Show Answer & Explanation ▾
✓ Correct Answer: B. 1 gm
The standard dose is 11 mg (base)/kg (maximum, 1 g), given orally once with or without food. For pinworm, the dose is repeated in 2 weeks, and cure rates are greater than 95%. The drug is available in the USA without prescription for this indication. For ascariasis, a single dose yields cure rates of 85–100%. Treatment should be repeated if eggs are found 2 weeks after treatment. For hookworm infections, a single dose is effective against light infections; but for heavy infections, especially with Necator americanus, a 3-day course is necessary to reach 90% cure rates. A course of treatment can be repeated in 2 weeks. Reference: LANG' Basic & clinical pharmacology by Bertram G. Katzung, Susen B. Masters and Anthony J. Trevor 12 th edition. Chapter 53-Clinical Pharmacology of the Antihelminthic Drugs by Dr. Philip J. Rosenthal, MD. Page no. 945
Sample MCQ #3
A patient presented with an episode of seizure and CT scan revealed presence of calcified cysts in brain with no evidence of Hydrocephalus. A diagnosis of Neurocysticercosis was made. Which of the following statements regarding treatment of this condition is correct?
AOnly anti parasitic drugs should be given
BAnti parasitic drugs should be given and after the completion of course, Steroids should be given
CSteroids should be started first followed by anti parasitic drugs
DOnly anti epileptic drugs should be given
Show Answer & Explanation ▾
✓ Correct Answer: C. Steroids should be started first followed by anti parasitic drugs
Steroids to be given first to prevent any hyperinflammatory syndrome due to dying parasites from Albendazole treatment. Neurocysticercosis: When albendazole/praziquantel is used to kill cysticerci lodged in the brain, prednisolone 40 mg/day or equivalent is given for 2-4 weeks to suppress the reaction to the dying larvae. All other options are not the correct ways to treat the patient.
Sample MCQ #4
A 35 years old male patient came to OPD with the complaints of diarrhoea, mild fever and weakness. His pulse rate is 100/min and BP is 100/70 mm Hg. He is already treated with antibacterial drugs which did not work. Physician is suspecting amebiasis. Which is the drug of choice for the treatment of extraluminal amebiasis?
AOfloxacin
BMetronidazole
CMeropenem
DAll of the above
Show Answer & Explanation ▾
✓ Correct Answer: B. Metronidazole
Metronidazole, a nitroimidazole, is the drug of choice in the treatment of extraluminal amebiasis. Reference: LANG' Basic & clinical pharmacology by Bertram G. Katzung, Susen B. Masters and Anthony J. Trevor 12 th edition. Chapter 52- Antiprotozoal Agents by Dr. Philip J. Rosenthal, MD. Page no. 927
Sample MCQ #5
Metronidazole acts by killing __________.
ACysts of E histolytica
BTrophozoites of E histolytica
CBoth of them
DNone of the above
Show Answer & Explanation ▾
✓ Correct Answer: B. Trophozoites of E histolytica
Metronidazole, a nitroimidazole, is the drug of choice in the treatment of extraluminal amebiasis. It kills trophozoites but not cysts of E histolytica and effectively eradicates intestinal and extraintestinal tissue infections. Reference: LANG' Basic & clinical pharmacology by Bertram G. Katzung, Susen B. Masters and Anthony J. Trevor 12 th edition. Chapter 52- Antiprotozoal Agents by Dr. Philip J. Rosenthal, MD. Page no. 927,928
Sample MCQ #6
Which of the following sentences are TRUE for administration of Albendazole? 1. It should be taken on empty stomach for intraluminal parasites 2. It should be taken with fatty meals for intraluminal parasites 3. It should be taken on empty stomach for tissue parasites 4. It should be taken with fatty meals for tissue parasites
A1,3
B2,4
C1,4
D2,3
Show Answer & Explanation ▾
✓ Correct Answer: C. 1,4
Albendazole is administered on an empty stomach when used against intraluminal parasites but with a fatty meal when used against tissue parasites. Reference: LANG' Basic & clinical pharmacology by Bertram G. Katzung, Susen B. Masters and Anthony J. Trevor 12 th edition. Chapter 53-Clinical Pharmacology of the Antihelminthic Drugs by Dr. Philip J. Rosenthal, MD. Page no. 938
Sample MCQ #7
Ivermectin is an alternate drug for multiple helminthic infections but it is drug of choice for ___________.
AStrongyloidiasis
BOnchocerciasis
CA&B both
DPneumocystis pneumonia
Show Answer & Explanation ▾
✓ Correct Answer: C. A&B both
Ivermectin is the drug of choice in strongyloidiasis and onchocerciasis. It is also an alternative drug for a number of other helminthic infections. Reference: LANG' Basic & clinical pharmacology by Bertram G. Katzung, Susen B. Masters and Anthony J. Trevor 12 th edition. Chapter 53-Clinical Pharmacology of the Antihelminthic Drugs by Dr. Philip J. Rosenthal,MD. Page no. 940
Sample MCQ #8
Diethylcarbamazine (DEC) is the drug of choice for________.
AFilariasis
BLoiasis
CTropical eosinophilia
DAll of the above
Show Answer & Explanation ▾
✓ Correct Answer: D. All of the above
Diethylcarbamazine is a drug of choice in the treatment of filariasis, loiasis, and tropical eosinophilia. It has been replaced by ivermectin for the treatment of onchocerciasis. Reference: LANG' Basic & clinical pharmacology by Bertram G. Katzung, Susen B. Masters and Anthony J. Trevor 12 th edition. Chapter 53-Clinical Pharmacology of the Antihelminthic Drugs by Dr. Philip J. Rosenthal,MD. Page no. 939
What you can practise in Anti-Protozoal Agents and Anthelmintic Drugs
23 Anti-Protozoal Agents and Anthelmintic Drugs MCQs on Anti-Protozoal Agents, Anthelmintic Drugs, Antimicrobials — each with detailed explanations
Previous-year question practice across NEET PG, FMGE, INI-CET and NEET SS
Progress and performance tracking to measure retention
What do Anti-Protozoal Agents and Anthelmintic Drugs MCQs cover?
Anti-Protozoal Agents and Anthelmintic Drugs MCQs run from metronidazole in amoebiasis and neurocysticercosis steroids to albendazole dosing, ivermectin and DEC in filariasis. These high-yield NEET PG questions on parasites, worms and their drug targets.
How many Anti-Protozoal Agents and Anthelmintic Drugs questions are there, and which exams do they cover?
MedLadder includes 23 curated MCQs for Anti-Protozoal Agents and Anthelmintic Drugs under Pharmacology (Antimicrobials), covering NEET PG, FMGE, INI-CET and NEET SS preparation.
