Neoplasms of Liver and Biliary Tract MCQs

Answer- A. Focal nodular hyperplasia Focal nodular hyperplasia is a rare tumor-like condition predominantly found in women during to third to the fifth decade of life. Most commonly it is incidentally discovered as asymptomatic mass. The pathognomonic microscopic feature. A central stellate scar seen in liver imaging studies is a highly characteristic feature of focal nodular hyperplasia. It is also seen in Renal cell carcinoma(RCC).

The tumor derived from bile ducts is a cholangiocarcinoma, which commonly occurs in cirrhotic livers, often in combination with hepatocellular carcinoma (A). The tumor has a poor prognosis (B). Hepatocellular carcinomas are most frequently associated with an elevation of α-fetoproteins; in fact, patients with cirrhosis of the liver, a risk factor for the development of hepatocellular carcinoma, can be followed with serial α-fetoproteins to monitor for the possible development of the tumor (although ultrasound imaging is preferred) (C). Primary sclerosis cholangitis, which occurs in a large proportion of patients with ulcerative colitis, is a significant risk factor for cholangiocarcinoma, along with Opisthorchis sinensis infection (D). Reference: Robbins Basic Pathology, 10 th ed, Pg-669