Antenatal Investigations MCQs

Complete gonadal dysgenesis is also known as SWYER SYNDROME. In this approximately 15-20% of patients, the disorder results from an inactivating point mutation in SRY gene, but in most cases cause is not known. (Deletion in SRY gene's DNA binding region 2 is present in 10-20 % of women)

Artificial rupture of membranes is C/I in polyhydramnios as it leads to sudden decompression of the uterus which can cause abruptio placenta. Method of induction in these patients is: low rupture of the membranes is done when the lie becomes stable and the presenting part gets fixed to the pelvis. This will minimize sudden decompression with separation of the placenta, change in lie of the fetus and cord prolapse. a stabilizing oxytocin infusion is started to check the favorable lie and presentation of the fetus drainage of good amount of liquor Amniocentesis Reference : Dutta Obs 7/e, pg 215

Answer- C. ANC USG Nuchal translucency is used for screening of down syndrome in antenatal USG.

Embryonic investigations suggest that cardiac contractions begin in the fetus at 36 days gestational age.' Cardiac activity should be detected routinely when the embryo attains a length of 4 to 5 mm. This corresponds to a GA of 6.0 to 6.5 weeks, at which time the MSD is 13 to 18 mm. Using a transabdominal approach, cardiac activity should be evident by 8 weeks GA, when the MSD is 25 mm.' Reference: USG in Obs. and Gynae. Callen 4/e, p 119, 120

Important causes of puberty menorrhagia are: HPO axis immaturity (anovulation) Bleeding disorders Endocrinological causes Hence TSH, platelet count and BT/CT are done S. estradiol levels are of no utility in the workup of this patient. Note: Always rule out bleeding disorder in patients of puberty menorrhagia Reference : Dutta Gynae 6 th /ed, pg no: 55