Renal Tubular Diseases of Kidney is part of the Renal System section of Medicine. Practise 20 exam-style MCQs for NEET PG, FMGE, INI-CET and NEET SS, each with the correct answer and a detailed explanation.
Renal Tubular Diseases of Kidney MCQs contrast hypokalaemic distal renal tubular acidosis with proximal tubular acidosis, and probe the drugs that injure tubules through interstitial nephritis, in high-yield NEET PG and FMGE revision.
Sample Renal Tubular Diseases of Kidney MCQs with answers
Sample MCQ #1
A 75-year-old man visits his GP for a new-patient screen. His only previous complaints have been type-2 diabetes and mild long-standing back pain. Screening tests reveal an elevated serum creatinine of 2.15 mg/dl and anaemia with Hb of 10.1 g/dl. A back X-ray shows collapse of the lumbar spine and there is a monoclonal band on serum protein electrophoresis. What is the most likely cause of his deteriorated renal function?
ADiabetic nephropathy
BMembranous glomerulonephritis
CMetformin toxicity
DAmyloidosis
Show Answer & Explanation ▾
✓ Correct Answer: D. Amyloidosis
This patient is suffering from Myeloma as evidenced by the presence of anemia, renal impairment and bone involvement. Myeloma can affect the kidney in several ways - the filtered light chains are toxic to the tubules and can cause acute obstruction: Cast nephropathy The light chain impairs the proximal tubular function and cause RTA Hypercalcemia can cause tubulointerstitial disease Amyloidosis LCDD All forms of renal involvement is reversible to a certain extend with treatment of myeloma. Among the given options Amyloidosis is the best pick Amyloidosis presents predominantly between the ages of 60 and 70 years. Reference: Harrison's Principles of Internal Medicine, 21 st edition, Ch:111, Pg:870.
Sample MCQ #2
A 55-year-old man with a history of hypertension has renal impairment. His creatinine is 2.8 mg/dl. Urine dipstick shows blood ++ and protein +. What is the most useful investigation?
AIntravenous urogram
BRenal ultrasound
CRenal biopsy
DDTPA scan
Show Answer & Explanation ▾
✓ Correct Answer: C. Renal biopsy
A urinalysis of 2+ blood and 1+ protein are strong pointers towards glomerular disease. Hence among the options, biopsy is the most useful investigation. Renal ultrasound may be useful in assessing the kidney size and echoes, but it may not help us arrive at a diagnosis. IV urogram is used in the investigation of Obstruction to urinary tract and DTPA nucleide scan is used to asses the functional status of kidneys. Indications of Renal biopsy(when suspected): Glomerulonephritis Nephrotic Syndrome Vasculitis Interstitial nephritis Myeloma kidney HUS and TTP Allograft rejection Reference: Harrison's Principles of Internal Principles, 21 st edition, Ch: 310, Pg: 2305.
Sample MCQ #3
Which of the following drugs cause renal impairment by causing interstitial nephritis?
AAminoglycosides
BVancomycin
CAmphotericin B
DQuinolones
Show Answer & Explanation ▾
✓ Correct Answer: D. Quinolones
Quinolones, penicillins, cephalosporins, sulphonamides and rifampicin are antibiotics that cause interstitial nephritis. Vancomycin, Aminoglycosides, Amphotericin B, Acyclovir, Foscarnet, Tenofovir and Cidofovir are toxic to the tubules of kidney. Vancomycin and acyclovir cause intra tubular obstruction. Amphotericin B causes RTA like picture with hypomagnesemia, hypocalcemia. Hypomagnesemia is also seen with Aminoglycosides. Reference: Harrison's Principles of Internal Medicine 21st ed, Chap 310, Pg. 2300
Sample MCQ #4
Which type of malaria is associated with renal failure -
AFalciparum
BVivax
CMalariae
DOvale
Show Answer & Explanation ▾
✓ Correct Answer: A. Falciparum
Ans. is 'a' i.e., Falciparum Nephrotic syndrome —> quarta malaria (P. malariae) Acute tubular necrosis (renal failure) malignant tertian malaria or pernicious malaria (caused by P falciparum).
Sample MCQ #5
Which of the following is not a cause of hypokalemic distal (type 1) renal tubular acidosis?
ASjogren's syndrome
BPrimary biliary cirrhosis
CAmphotericin B
DHypogammaglobulinemia
Show Answer & Explanation ▾
✓ Correct Answer: D. Hypogammaglobulinemia
Hypergammaglobulinemia causes hyperkalemic distal renal tubular acidosis hypogammaglobulinemia is not reported to cause the distal renal tubular acidosis Reference: Harrisons Principles of Internal Medicine, 21 st Ed, Ch:55 Pg: 364
Sample MCQ #6
Which of the following drugs cause proximal RTA?
AIfosfamide
BAmphotericin B
CStreptomycin
DVancomycin
Show Answer & Explanation ▾
✓ Correct Answer: A. Ifosfamide
Proximal RTA is caused by Ifosfamide, Streptozocin, outdated tetracyclines, gentamicin and Tenofovir. Amphotericin B causes distal RTA. Reference: Harrison's Principles of Internal Medicine 21st ed, Chap 310, Pg. 2301
What you can practise in Renal Tubular Diseases of Kidney
20 Renal Tubular Diseases of Kidney MCQs on Renal Tubular Diseases, Kidney, Renal System — each with detailed explanations
Previous-year question practice across NEET PG, FMGE, INI-CET and NEET SS
Progress and performance tracking to measure retention
What do Renal Tubular Diseases of Kidney MCQs cover?
Renal Tubular Diseases of Kidney MCQs contrast hypokalaemic distal renal tubular acidosis with proximal tubular acidosis, and probe the drugs that injure tubules through interstitial nephritis, in high-yield NEET PG and FMGE revision.
How many Renal Tubular Diseases of Kidney questions are there, and which exams do they cover?
MedLadder includes 20 curated MCQs for Renal Tubular Diseases of Kidney under Medicine (Renal System), covering NEET PG, FMGE, INI-CET and NEET SS preparation.
