Cardiomyopathy and Myocarditis is part of the Cardiovascular System section of Medicine. Practise 28 exam-style MCQs for NEET PG, FMGE, INI-CET and NEET SS, each with the correct answer and a detailed explanation.
Cardiomyopathy and Myocarditis MCQs move from dilated cardiomyopathy in end-stage failure through infective causes of myocardial injury to fever, cervical adenopathy and conjunctival congestion pointing toward Kawasaki disease, a NEET PG high-yield cluster.
Sample Cardiomyopathy and Myocarditis MCQs with answers
Sample MCQ #1
Which is not correct regarding RA?
AThe incidence of RA increases between 25 and 55 years of age, after which it plateaus until the age of 75 and then decreases
BThe most common pattern of joint involvement is symmetrical and polyarticular.
CFlexor tendon tenosynovitis is a frequent hallmark of RA
DMacrocytic anemia is the most common hematologic abnormality in RA
Show Answer & Explanation ▾
✓ Correct Answer: D. Macrocytic anemia is the most common hematologic abnormality in RA
A normochromic, normocytic anemia often develops in patients with RA and is the most common hematologic abnormality. Macrocytic anemia may occur in RA due to Methotrexate toxicity. Flexor tenosynovitis can occur in RA. It causes trigger fingers. The most common tendon involved is Flexor Pollicis Longus. The age of onset of RA is between 25 to 55 years of age, after which it plateaus until the age of 75 , after which it decreases. The most common pattern of involvement is symmetrical, polyarthritis. DIP is usually not involved, but if so, it is often due to OA. Reference: Harrison's Principles of Internal Medicine 21st edition Ch:358 Pg:2753
Sample MCQ #2
Which of the following drugs target TNF ?
AEtanercept
BAbatacept
CAnakinra
DTocilizumab
Show Answer & Explanation ▾
✓ Correct Answer: A. Etanercept
Etanercept is an Anti TNFα agent used in the management of RA. TNFα agents used in the management of RA includes: Monoclonal antibodies: Infliximab, Adalimumab, Golumumab and Certrolizumab pegol Etanercept is a soluble fusion protein comprising of TNFα receptor 2 in covalent linkage with Fc portion of IgG. Reference: Harrison's Principles of Internal Medicine, 21st ed, Ch: 358, Pg: 2761
Sample MCQ #3
Which drugs are unsafe and unequivocally contraindicated during pregnancy in a RA patient? 1. HCQ 2. Methotrexate 3. Sulfasalazine 4. Leflunomide 5. TNF alpha inhibitors 6. Glucocorticoids Choose the correct combinations of unsafe drugs?
A2, 3, 4, 5
B1, 2, 3, 4
C2, 4
D2, 4, 5
Show Answer & Explanation ▾
✓ Correct Answer: C. 2, 4
Flares during pregnancy are generally treated with low doses of prednisone; hydroxychloroquine and sulfasalazine are probably the safest DMARDs to use during pregnancy. Methotrexate and leflunomide therapy are contraindicated during pregnancy due to their teratogenicity in animals and humans. Biologicals are thought to be safe in the second trimester. Reference: Harrison's Principles of Internal Medicine 21st edition, Ch:358, Pg:2765
Sample MCQ #4
A 5 year old boy presents with history of fever of 1 week duration, along with bilateral cervical adenopathy, bilateral conjunctival congestion, erythema of the oral cavity and desquamation, especially of the finger tips. He has evidence of myocarditis too. He has an ESR of 100mm/1st hour, elevated CRP, and elevated liver enzymes. Which infection will you suspect?
AChlamydia
BCOVID 19
CMeasles
DRubella
Show Answer & Explanation ▾
✓ Correct Answer: B. COVID 19
This patient presents with a multi system involvement. The salient features are involvement of mucosa and desquamation of the skin especially the finger tips. He also has myocarditis. This fits into the picture of Kawazaki Disease. An infection which presents with clinical features resembling Kawazaki Disease is MIS-C, caused by COVID 19. Reference: Harrison’s Principles of Internal Medicine 21 st edition Ch:363 Pg:2816
Sample MCQ #5
A 65-year-old male attends a clinic complaining of breathlessness and persistent fatigue. He has end stage cardiac failure due to dilated cardiomyopathy. Currently he takes Furosemide, Lisinopril, Spironolactone and Carvedilol. Which one of the following drugs should be added to his current therapy?
ADiltiazem
BDigoxin
CIsosorbide Mononitrate
DNicorandil
Show Answer & Explanation ▾
✓ Correct Answer: B. Digoxin
Digoxin has a positive inotropic effect; it can be used in patients with heart failure who are in sinus rhythm but presenting with severe symptoms with no response to guideline mediated medical therapy including an ACE inhibitor, diuretic and beta blocker. Digoxin has a narrow therapeutic window, hence should be used cautiously to avoid the risk of serious adverse effects including arrhythmias. Reference : Harrison's Principles of Internal Medicine 21 st edition Page 1946
Sample MCQ #6
Which of the following is not true regarding dilated cardiomyopathy?
AFunctional mitral regurgitation may be seen
BIncreased atrial size
CEjection fraction is usually preserved till later stages
DLeft sided failure occurs earlier than right sided heart failure
Show Answer & Explanation ▾
✓ Correct Answer: C. Ejection fraction is usually preserved till later stages
Dilated cardiomyopathy Ejection fraction is usually significantly reduced ( Left ventricular wall thickness is reduced with increase in LV diastolic dimension Mitral regurgitation is commonly seen due to annular and atrial dilatation Left sided symptoms are predominantly present unlike restrictive cardiomyopathy which presents with right predominant disease Most common cause is ischemic followed by infectious, toxin related, inflammatory and endocrine diseases related. Reference : Harrison's Principles of Internal Principles, 21 st edition, pg:1955
Sample MCQ #7
Which of the following is the most common infective cause of cardiomyopathy?
AHIV infection
BChagas disease
CDiphtheria
DCoxsackie virus infection
Show Answer & Explanation ▾
✓ Correct Answer: B. Chagas disease
Chagas disease, caused by Trypanosoma cruzi and transmitted by reduviid bug is the most common infectious cause of cardiomyopathy. Typical features include conduction system abnormalities commonly AV blocks Parvovirus B19, Coxsackie and Echoviruses are the most common infectious causes of myocarditis Bacterial causes of myocarditis include legionella, salmonella, Corynebacterium diphtheria etc Reference : Harrison's Principles of Internal Medicine 21 st edition Page 1972
Sample MCQ #8
A 55-year-old man with a longstanding history of alcohol excess has had a progressive abdominal distension for several months.On physical examination he has a non-tender abdomen with no masses palpable, but there is a fluid thrill. An abdominal ultrasound scan shows a large abdominal fluid collection with a small cirrhotic liver. A chest x ray shows increased cardiothoracic ratio with bilateral pleural effusion. Which of the following conditions is most likely to be present?
ADilated cardiomyopathy
BLymphocytic myocarditis
CMyocardial amyloid deposition
DConstrictive pericarditis
Show Answer & Explanation ▾
✓ Correct Answer: A. Dilated cardiomyopathy
Alcohol when consumed in significant amounts for 5-10 years is a risk factor for development of alcohol induced cardiomyopathy which presents with features of dilated cardiomyopathy. Toxicity is attributable to acetaldehyde, the primary metabolite of ethanol. Reference : Harrison's Principles of Internal Medicine, 21 st ed, Ch: 259, Pg: 1959
What you can practise in Cardiomyopathy and Myocarditis
28 Cardiomyopathy and Myocarditis MCQs on Cardiomyopathy, Myocarditis, Cardiovascular System — each with detailed explanations
Previous-year question practice across NEET PG, FMGE, INI-CET and NEET SS
Progress and performance tracking to measure retention
What do Cardiomyopathy and Myocarditis MCQs cover?
Cardiomyopathy and Myocarditis MCQs move from dilated cardiomyopathy in end-stage failure through infective causes of myocardial injury to fever, cervical adenopathy and conjunctival congestion pointing toward Kawasaki disease, a NEET PG high-yield cluster.
How many Cardiomyopathy and Myocarditis questions are there, and which exams do they cover?
MedLadder includes 28 curated MCQs for Cardiomyopathy and Myocarditis under Medicine (Cardiovascular System), covering NEET PG, FMGE, INI-CET and NEET SS preparation.
