Muscle Physiology I is part of the Nerve Muscle Physiology section of Physiology. Practise 52 exam-style MCQs for NEET PG, FMGE, INI-CET and NEET SS, each with the correct answer and a detailed explanation.
DHPR–ryanodine coupling, titin spanning Z-line to M-line and dystrophin loss in Duchenne dystrophy anchor these Muscle Physiology I MCQs, which contrast red and white fibres for high-yield NEET PG revision.
Sample Muscle Physiology I MCQs with answers
Sample MCQ #1
Duration of maximum contraction depends upon
AAbsolute refractive period
BRelative refractive period
CBoth
DNone of the two
Show Answer & Explanation ▾
✓ Correct Answer: B. Relative refractive period
Absolute refractory period No stimulus, no matter how strong, will not excite the muscle during absolute refractory period - No contraction possible Relative refractory period Stronger than normal stimulus (suprathreshold stimulus) produces action potential in relative refractory period - contraction possible Reference: Ganong, 25th edition/page no.101
Sample MCQ #2
In skeletal muscle DHPR & RYR receptors are coupled by?
AChemically
BMechanically
CChemical followed by electrical
DElectrical
Show Answer & Explanation ▾
✓ Correct Answer: B. Mechanically
In skeletal muscle DHPR & RYR receptors are coupled mechanically. The membrane of T-tubules contains voltage-gated Ca2+ channels called dihydropyridine (DHP) receptors. When the action potential reaches the tip of Ttubule, it activates the DHP receptors. Activated DHP receptors in turn trigger the opening of Ca2+ release channels located on the terminal cisterns known as ryanodine receptors (RYR). This is possible as the lateral cisterns are located very close to the tips of T-tubules and the protein channels of the cisterns i.e DHP and RYR are mechanically interlocked.
Sample MCQ #3
Smooth muscle cell membrane is
ASarcoplasm
BSarcolemma
CSarcomere
DSarcoplasmic reticulum
Show Answer & Explanation ▾
✓ Correct Answer: B. Sarcolemma
The cell membrane of muscle fibers in general is called as sarcolemma Reference: Ganong, 25th edition/page no.115
Sample MCQ #4
The nerve impulse which leads to initiation of smooth muscle contraction
ACause opening of the calcium channel which leads to increase in Ca2+ contraction
BCause both plasma membrane and T - tubules to undergo depolarisation
CInhibits Na+ entry in sarcomere
DIs initiated by binding of acetylcholine to receptors in sarcoplasmic reticulum
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✓ Correct Answer: A. Cause opening of the calcium channel which leads to increase in Ca2+ contraction
The nerve impulse which leads to initiation of smooth muscle contraction Cause opening of the calcium channel which leads to increase in Ca2+ concentration. Reference: Ganong, 25th edition/page no.116
Sample MCQ #5
Absent of dystrophin protein in muscle fiber causes:
ADuchenne muscular dystrophy
BBecker muscle dystrophy
CMyotonic dystrophy
DTibialis myopathies
Show Answer & Explanation ▾
✓ Correct Answer: A. Duchenne muscular dystrophy
Absence of dystrophin protein leads to Duchenne muscular dystrophy Reference: Ganong, 25th edition page no.101
Sample MCQ #6
Protein connecting Z - lines to M - lines
AKinin
BDesmin
CTitin
DActin
Show Answer & Explanation ▾
✓ Correct Answer: C. Titin
Titin It is the largest known protein present in mammals Also called as "muscle spring" because it is responsible for "Elasticity" in muscle connects the Z lines to the M lines and provides scaffolding for the sarcomere Reference: Ganong, 25th edition page no.100
Sample MCQ #7
All are true about red muscle fibers except
AMore mitochondria
BGlycolytic metabolism
CMore myoglobin
DMore oxidative capacity
Show Answer & Explanation ▾
✓ Correct Answer: B. Glycolytic metabolism
Red muscle fibers depend mainly on aerobic metabolism White muscle fibers depend mainly on anaerobic metabolism Reference: Ganong, 25th edition page no.108
Sample MCQ #8
Which of the following is not a Sarcolemmal protein?
ASarcoglycan
BDystrophin
CDystroglycan
DPerlecan
Show Answer & Explanation ▾
✓ Correct Answer: D. Perlecan
Dystrophin-Glycoprotein complex: adds strength to the muscle by providing a scaffolding for the fibrils and connecting them to the exterior Its components are dystroglycan, merosin, syntrophins and sarcoglycan Perlecan - it is the extracellular matrix proteoglycan Reference: Ganong, 25th edition/page no.100
What you can practise in Muscle Physiology I
52 Muscle Physiology I MCQs on Nerve Muscle Physiology — each with detailed explanations
Previous-year question practice across NEET PG, FMGE, INI-CET and NEET SS
Progress and performance tracking to measure retention
DHPR–ryanodine coupling, titin spanning Z-line to M-line and dystrophin loss in Duchenne dystrophy anchor these Muscle Physiology I MCQs, which contrast red and white fibres for high-yield NEET PG revision.
How many Muscle Physiology I questions are there, and which exams do they cover?
MedLadder includes 52 curated MCQs for Muscle Physiology I under Physiology (Nerve Muscle Physiology), covering NEET PG, FMGE, INI-CET and NEET SS preparation.
