Antimicrobials Acting on 30S Subunit is part of the Antimicrobials section of Pharmacology. Practise 7 exam-style MCQs for NEET PG, FMGE, INI-CET and NEET SS, each with the correct answer and a detailed explanation.
Antimicrobials Acting on 30S Subunit MCQs examine aminoglycoside action against aerobic gram-negative infection, with irreversible ribosomal binding at the core. A compact high-yield NEET PG set on protein synthesis inhibitors and their clinical reach.
Sample Antimicrobials Acting on 30S Subunit MCQs with answers
Sample MCQ #1
A 67-year-old man develops dysuria, flank pain, and fever. Examination shows marked tenderness in the right costovertebral area. Treatment with an antibiotic is begun, but his symptoms do not improve. Further evaluation shows that the causal organism produces an enzyme that inactivates the antibiotic via phosphorylation. An agent from which of the following classes of antibiotics was most likely administered?
AAminoglycosides
BTetracycline
CFluoroquinolones
DMacrolides
Show Answer & Explanation ▾
✓ Correct Answer: A. Aminoglycosides
This antibiotic is used to treat infections with gram-negative, aerobic bacteria and acts by irreversibly inhibiting the 30S subunit of the initiation complex. Aminoglycosides are bactericidal agents that inhibit bacterial protein synthesis by binding to the 30S ribosomal subunit. Microbial resistance develops when enzymes (e.g., transferases) are produced that inactivate the antibiotic via phosphorylation, acetylation, or adenylation. Aminoglycosides, which are effective against gram-negative bacilli (e.g., E.coli, Klebsiella, Serratia, Proteus, Pseudomonas), can be used instead of fluoroquinolones for the inpatient treatment of complicated pyelonephritis. Reference: Basic & Clinical Pharmacology, Fourteenth Edition By Bertram G. Katzung Pg. no. 839
What you can practise in Antimicrobials Acting on 30S Subunit
7 Antimicrobials Acting on 30S Subunit MCQs on Pharmacology — each with detailed explanations
Previous-year question practice across NEET PG, FMGE, INI-CET and NEET SS
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What do Antimicrobials Acting on 30S Subunit MCQs cover?
Antimicrobials Acting on 30S Subunit MCQs examine aminoglycoside action against aerobic gram-negative infection, with irreversible ribosomal binding at the core. A compact high-yield NEET PG set on protein synthesis inhibitors and their clinical reach.
How many Antimicrobials Acting on 30S Subunit questions are there, and which exams do they cover?
MedLadder includes 7 curated MCQs for Antimicrobials Acting on 30S Subunit under Pharmacology (Antimicrobials), covering NEET PG, FMGE, INI-CET and NEET SS preparation.