General Principles of Endocrinology is part of the Endocrine System section of Medicine. Practise 70 exam-style MCQs for NEET PG, FMGE, INI-CET and NEET SS, each with the correct answer and a detailed explanation.
From the suprachiasmatic control of diurnal ACTH rhythm to thelarche as the opening pubertal milestone and the cholinergic warning signs of hypoglycaemia, these General Principles of Endocrinology MCQs link hormone physiology with bedside recognition — high-yield groundwork for NEET PG, FMGE and INI-CET.
Sample General Principles of Endocrinology MCQs with answers
Sample MCQ #1
A 14 year old boy develops red eye and rhinitis frequently during the start of the summer. What is the likely triggering agent?
AHouse dust mite
BGrass pollen
CWillow pollen
DIsocyanates
Show Answer & Explanation ▾
✓ Correct Answer: B. Grass pollen
Grass pollen is released late May till August, and willow pollen is released from March till June. As the allergic rhinitis is triggered during the start of summer, this is most likely to be due to grass pollen. Reference : Harrison's Principles of Internal medicine, 21st edition Ch:288 Pg 2160
Sample MCQ #2
Diurnal variation of ACTH depends on ?
ASuprachiasmatic nucleus
BSupraoptic nucleus
CVentrolateral nucleus
DThalamus
Show Answer & Explanation ▾
✓ Correct Answer: A. Suprachiasmatic nucleus
Ans. A. Suprachiasmatic nucleus The biologic clock responsible for the diurnal ACTH rhythm is located in the suprachiasmatic nuclei of the hypothalamus.
Sample MCQ #3
A 14-year-old girl is seen at the endocrine clinic because her mother is concerned that her daughter's periods have not yet started. In reviewing her history, which of the following would be most typical of the first sign of onset of puberty?
APubic hair growth
BBreast-bud development
CAxillary hair growth
DMenarche
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✓ Correct Answer: B. Breast-bud development
Breast-bud enlargement (thelarche) is the first sign of puberty in girls. The average age of pubertal onset is earlier in girls than boys. The order of pubertal progression in females is thelarche, pubarche followed by menarche. Reference : Harrison's Principles of Internal Medicine 21 st edition Page 3031
Sample MCQ #4
Patient with 70% burns. A test was done on a sample collected from the burns site is shown below. An obligate aerobe bacteria was isolated from the burns victim. What is the likely organism?
APseudomonas
BE.Coli
CKlebsiella
DNone
Show Answer & Explanation ▾
✓ Correct Answer: A. Pseudomonas
The dead tissue and moist environment of a burn wound creates an ideal environmentfor Pseudomonas to thrive. Burn trauma can cause immunosuppression, which makes the body more susceptible to microbial colonization. Burn site infection Obligate aerobe Two of the identifying biochemical characteristics of P. aeruginosa are an inability to ferment lactose on MacConkey agar and a positive reaction in the oxidase test
Sample MCQ #5
Which of the following is a cardioselective beta blocker?
APropranolol
BAtenolol
CCarvedilol
DLabetolol
Show Answer & Explanation ▾
✓ Correct Answer: B. Atenolol
The cardioselective beta blockers include: Bisoprolol Acebutolol Atenolol Metoprolol Esmolol Reference : Ladage D, Schwinger RH, Brixius K. Cardio-selective beta-blocker: pharmacological evidence and their influence on exercise capacity. Cardiovasc Ther. 2013 Apr;31(2):76-83.
Sample MCQ #6
What is the grade of dyspnea in a cardiac patient with breathlessness on going to the Washroom?
ANYHA grade 2
BNYHA grade 3
CMMRC grade 2
DMMRC grade 3
Show Answer & Explanation ▾
✓ Correct Answer: B. NYHA grade 3
Dyspnea on exertion at less than ordinary activity is NYHA grade 3
Sample MCQ #7
Which of the following is not a cholinergic symptom of hypoglycemia?
ASweating
BPalpitation
CHunger
DParesthesias
Show Answer & Explanation ▾
✓ Correct Answer: B. Palpitation
Cholinergic symptoms of hypoglycemia, mediated by acetylcholine which is released from sympathetic postganglionic neurons are sweating, hunger and paresthesia. Adrenergic symptoms mediated by norepinephrine which is released from sympathetic postganglionic neurons and epinephrine released from the adrenal medulla are the tremor, anxiety, palpitations. Reference: Harrison 20 th chap 399 pg. 2884
Sample MCQ #8
A patient who is on Amphotericin B developed weakness and cramps.The serum potassium was 2.3 mEq/dl. Calculate the total parenteral potassium supplementation to be prescribed to the patient over the next 24 hours?
A60mEq
B80mEq
C100mEq
D140 mEq
Show Answer & Explanation ▾
✓ Correct Answer: D. 140 mEq
For causing a rise of potassium in blood by 1mEq/dl ,200 mEq of potassium supplementation is needed.Since symptoms develop with serum potassium less than 3mEq/dl the clinician should provide sufficient potassium to rise up to 3mEq/dl through the IV route. Following oral potassium supplement will suffice.Therefore, mathematically speaking this patient needs approximately 0.7 mEq/dl of potassium to rise in the blood resulting in a requirement of 0.7 x 200 = 140 mEq OVER 24hrs. Reference: Harrison 20 th chap 49 pg.308
What you can practise in General Principles of Endocrinology
70 General Principles of Endocrinology MCQs on Principles, Endocrinology, Endocrine System — each with detailed explanations
Previous-year question practice across NEET PG, FMGE, INI-CET and NEET SS
Progress and performance tracking to measure retention
What do General Principles of Endocrinology MCQs cover?
From the suprachiasmatic control of diurnal ACTH rhythm to thelarche as the opening pubertal milestone and the cholinergic warning signs of hypoglycaemia, these General Principles of Endocrinology MCQs link hormone physiology with bedside recognition — high-yield groundwork for NEET PG, FMGE and INI-CET.
How many General Principles of Endocrinology questions are there, and which exams do they cover?
MedLadder includes 70 curated MCQs for General Principles of Endocrinology under Medicine (Endocrine System), covering NEET PG, FMGE, INI-CET and NEET SS preparation.
