Pre-Embryonic Phase of Development is part of the Embryology section of Anatomy. Practise 17 exam-style MCQs for NEET PG, FMGE, INI-CET and NEET SS, each with the correct answer and a detailed explanation.
Pre-Embryonic Phase of Development MCQs trace fertilisation in the ampulla through cleavage, blastocyst formation and implantation, including trophoblast differentiation and the events of the second week — high-yield NEET PG groundwork for embryology.
Sample Pre-Embryonic Phase of Development MCQs with answers
Sample MCQ #1
Which of the following events are directly related to implantation?
AInteraction between uterine endometrium and hypoblast
BRelease of proteolytic enzymes
CLoss of the decidua
DAcrosome reaction
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✓ Correct Answer: B. Release of proteolytic enzymes
When the zona pellucida is lost, the blastocyst is able to release proteolytic enzymes that allow it to penetrate the uterine wall. The uterine mucosal lining also aids in promoting enzyme release. The acrosome reaction is not related to implantation in that it occurs before fertilization. Reference - Textbook of Langman's, 12th Edition, General Embryology Page number - 29
Sample MCQ #2
Cleavage divisions are always:
AMeiotic
BMitotic
CAmniotic
DAnucleotic
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✓ Correct Answer: B. Mitotic
The divisions that occur during cleavage are always mitotic, producing daughter cells with a diploid number of chromosomes. However, in cleavage there is no period of cell growth between divisions, so that the originally oversized ovum is fractionalized through cleavage into cells, called blastomeres, of normal size. Reference - Textbook of Langman's, 12th Edition, General Embryology Page number - 29
Sample MCQ #3
Which statement about the 14-day blastocyst is NOT true?
AVilli are absent
BExtraembryonic coelom surrounds the yolk sac
CPrimitive uteroplacental circulation is established
DNone of the above
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✓ Correct Answer: D. None of the above
If none of the above are not true, then all are true, which is true. Syncytiotrophoblast extends processes into the endometrium at the end of the 1st week, and spaces called lacunae or sinusoids appear within this syncytium during the 2nd week. Maternal blood leaking into the lacunae initiates uteroplacental circulation. Primary villi form near the end of 2 weeks as cytotrophoblast invades syncytium. Reference - Textbook of Langman's, 12th Edition, General Embryology Page number - 43
Sample MCQ #4
The outer layer of the blastocyst forms ?
APrimitive streak
BYolk sac
CEmbryo proper
DTrophoblast
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✓ Correct Answer: D. Trophoblast
Ans. is 'd' i.e.,Trophoblast [Ref Singh IB, Human embryology Stile p. 38] Blastocyst possesses an inner cell mass called embryoblast which subsequently forms the embryo proper, and an outer layer of cells, or trophoblast, which helps to provide nutrition to the embryo.
Sample MCQ #5
During the second week of development, the trophoblast differentiates into:
ASyncytiotrophoblast
BEctoderm
CIntraembryonic mesoderm
DYolk sac (secondary)
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✓ Correct Answer: A. Syncytiotrophoblast
The trophoblast gives rise to both the syncytiotrophoblast and the cytotrophoblast, as well as the extraembryonic mesoderm. The ectoderm is a derivative of the epiblast, and the secondary yolk sac comes from endoderm cells that line the exocoelomic cavity or the primitive yolk sac. Reference - Textbook of Langman's, 12th Edition, General Embryology Page number - 43
Sample MCQ #6
Blastocyst makes contact with endometrium on ?
A< 3 days
B5 - 7 days
C8 - 11 days
D15 -16 days
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✓ Correct Answer: B. 5 - 7 days
Ans. is 'b' i.e., 5 -7 days [Ref: Text book of Human embryology - 286] Contact of blastocyst with endometrium occurs at the time of implantation. Implantation occurs at around 6 -7 days. 11. Haploid number of chromosomes is seen in ? a) Spermatogonia b) Primary spermatocytes c) Secondary spermatocyte d) None Correct Answer - C Ans. is 'c' i.e., Secondary spermatocyte [Ref Ganong 23'd% p. 403, 404] Diploid means that cell contains 46 chromosomes (diploid of 23) and haploid means that cell contains 23 chromosomes. Development of sperm is as follows : - Spermatogonia(Diploid-46) → Primary spermatocyte (Diploid-46) Primary spermatocyte (Diploid-46) is of 2 types-
Sample MCQ #7
The meeting and union of human sex cells is believed to occur in the:
AUpper third of uterine tube
BMiddle third of uterine tube
CLower third of uterine tube
DUterus
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✓ Correct Answer: A. Upper third of uterine tube
Fertilization occurs in the upper third of uterine tube, a region called the ampullary region. The sperm are transported there primarily by muscular contractions and by action of the cilia in the uterine tube. Reference - Textbook of Langman's, 12th Edition, General Embryology Page number - 29
Sample MCQ #8
At the 32-cell stage of division, the embryo is known as a blastocyst that contains inner cell mass and outer cell mass. What do the inner and outer cell masses eventually become?
APlacenta / embryo and fetus
BEmbryo and fetus / placenta
CChorionic membrane / amniotic membrane
DAmniotic membrane / chorionic membrane
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✓ Correct Answer: B. Embryo and fetus / placenta
The inner cell mass of the blastocyst becomes the embryoblast and then eventually the embryo and fetus while the outer cell mass becomes trophoblast and then eventually the placenta. Reference - Textbook of Langman's, 12th Edition, General Embryology Page number - 29
What you can practise in Pre-Embryonic Phase of Development
17 Pre-Embryonic Phase of Development MCQs on Pre-Embryonic Phase, Development, Embryology — each with detailed explanations
Previous-year question practice across NEET PG, FMGE, INI-CET and NEET SS
Progress and performance tracking to measure retention
What do Pre-Embryonic Phase of Development MCQs cover?
Pre-Embryonic Phase of Development MCQs trace fertilisation in the ampulla through cleavage, blastocyst formation and implantation, including trophoblast differentiation and the events of the second week — high-yield NEET PG groundwork for embryology.
How many Pre-Embryonic Phase of Development questions are there, and which exams do they cover?
MedLadder includes 17 curated MCQs for Pre-Embryonic Phase of Development under Anatomy (Embryology), covering NEET PG, FMGE, INI-CET and NEET SS preparation.