Heart is part of the Thorax section of Anatomy. Practise 58 exam-style MCQs for NEET PG, FMGE, INI-CET and NEET SS, each with the correct answer and a detailed explanation.
Heart MCQs follow the heart tube from bilateral primordia through septation, the sinus venosus origins of the coronary sinus and right atrium, and the valves open during ventricular systole — high-yield NEET PG revision.
Sample Heart MCQs with answers
Sample MCQ #1
In the development of the cardiovascular system:
AAngiogenic clusters appear in the yolk sac endoderm
BThe midline heart tube forms four chambers
CThe aortic arches develop in a caudal to cephalic sequence
DThe heart begins to beat around the 21st day
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✓ Correct Answer: D. The heart begins to beat around the 21st day
Angiogenic cell clusters appear in mesoderm only. The heart arises as two bilateral tubes that eventually fuse into one heart tube that begins to beat around the 21st day. When the aortic arches develop, they do so in a cephalic to caudal direction. Reference - Textbook of Langman's, 12th Edition, Cardiovascular System Embryology Page number - 185
Sample MCQ #2
The myocardial layer of the heart tube develops from:
AThe endocardial tubes
BDorsal mesocardium
CCardiac jelly
DSplanchnic mesoderm
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✓ Correct Answer: D. Splanchnic mesoderm
Myocardium or heart muscle arises from the splanchnic mesoderm near the heart tubes in the cardiogenic region. Endocardium is also from this cardiogenic splanchnic mesoderm, from angiogenic cell clusters forming the heart tubes. Epicardium or visceral pericardium is from splanchnic mesoderm lining the intraembryonic coelom. Reference - Textbook of Langman's, 12th Edition, Cardiovascular System Embryology Page number - 185
Sample MCQ #3
The following are true statements with regard to the fetal circulation EXCEPT:
ASince the fetal liver is a hemopoietic organ, it is large and well supplied with oxygenated blood
BFetal brain receives relatively pure arterial blood
CFetal and maternal blood vessels anastomose in the placenta
DIn early developmental stages, one pulmonary vein buds from the left atrium of the heart
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✓ Correct Answer: C. Fetal and maternal blood vessels anastomose in the placenta
In the placenta, there is no anastomosis between the maternal and fetal vessels. Maternal blood from the spiral arteries enters the cotyledons, where it bathes the villi from the fetus. This all occurs without anastomosis. Reference - Textbook of Langman's, 12th Edition, Cardiovascular System Embryology Page number - 185
Sample MCQ #4
The fetal right atrium is mainly derived from:
APrimitive pulmonary vein
BPrimitive atrium
CRight pulmonary vein
DSinus venosus
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✓ Correct Answer: D. Sinus venosus
The right sinus horn of the sinus venosus enlarges and forms the fetal right atrium. The left sinus horn regresses to form the main vein draining the heart muscle, the coronary sinus. The original right atrium becomes the right auricle and also part of right atrium anterior to the crista terminalis. Reference - Textbook of Langman's, 12th Edition, Cardiovascular System Embryology Page number - 170
Sample MCQ #5
Coronary sinus develops from ?
ATruncus arteriosus
BConus
CSinus venosus
DAV canal
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✓ Correct Answer: C. Sinus venosus
Ans. is 'c' i.e., Sinus venosus [Ref Essentials of human embryology p. 873] The Coronary sinus develops from the Sinus venosus segment of embryonic heart. Left horn of sinus venosus retrogresses to form part of coronary sinus
Sample MCQ #6
From where the membranous part of the interventricular septum is derived from?
ALeft venous valve
BEndocardial cushion
CSeptum primum
DBulbous venosus
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✓ Correct Answer: B. Endocardial cushion
The structure marked is the membranous part of the interventricular septum. It is derived from endocardial cushions. Endocardial cushions are soft tissue masses that protrude in the atrioventricular and conotruncal regions. Atrioventricular cushions are derived from overlying endocardial cells. The conotruncal cushions are derived from the neural crest cells. Endocardial cushions contribute to the formation of: Atrial septa Ventricular septa (membranous portion) Atrioventricular canals Atrioventricular valves Aortic and pulmonary channels Reference - Textbook of Langman's, 12th Edition, Cardiovascular System Embryology Page number - 171
Sample MCQ #7
Which of the following structures ruptures to create the transverse pericardial sinus?
ASeptum primum
BSeptum secundum
CDorsal mesocardium
DTruncus arteriosus
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✓ Correct Answer: C. Dorsal mesocardium
Early in heart development, the heart tubes are suspended within the intraembryonic coelom by the dorsal mesocardium. The rupture of this membrane and the folding of the heart tubes brings the outflow tract and inflow tract close together, producing the transverse pericardial sinus. Reference - Textbook of Langman's, 12th Edition, Cardiovascular System Embryology Page number - 170
Sample MCQ #8
Which valves would be open during ventricular systole?
AAortic and pulmonary
BAortic and tricuspid
CMitral and aortic
DTricuspid and mitral
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✓ Correct Answer: A. Aortic and pulmonary
Remember that ventricular systole is the period when the ventricles are contracting. This contraction forces blood out of the heart, which pushes the aortic and pulmonary valves open. During systole, the tricuspid and mitral valves are closed. They are prevented from prolapsing (being pushed back into the atrium) by the chordae tendinae and papillary muscles Reference: Textbook of Gray's Anatomy for students, 3rd Edition, Thorax, Page number - 235
What you can practise in Heart
58 Heart MCQs on Thorax — each with detailed explanations
Previous-year question practice across NEET PG, FMGE, INI-CET and NEET SS
Progress and performance tracking to measure retention
Heart MCQs follow the heart tube from bilateral primordia through septation, the sinus venosus origins of the coronary sinus and right atrium, and the valves open during ventricular systole — high-yield NEET PG revision.
How many Heart questions are there, and which exams do they cover?
MedLadder includes 58 curated MCQs for Heart under Anatomy (Thorax), covering NEET PG, FMGE, INI-CET and NEET SS preparation.